Search results for "Surface shape"
showing 3 items of 3 documents
Optimization of the contact surface shape of a shrinkage fit
1998
Amongst many processes existing today for the assembly of two cylindrical parts, the shrinkage fit is commonly used. However, in the calculation methods, the contact surfaces are assumed to be perfect. Therefore, in order to apply these, the standards necessitate very small geometrical tolerances. The objective of the present paper is to show that it is possible to take into account form defects by closely conformed contact modelling and to have a good representation of reality: form defects always exist to an increasing extent and are inherent in all kinds of manufacturing processes. Finally, it is shown that the presence of defects can be beneficial, allowing optimization from both a mech…
Free-surface shape in unbaffled stirred vessels: Experimental study via digital image analysis
2013
There is a growing interest in using unbaffled stirred tanks for addressing a number of processing needs such as low shear damage (sensitive biocultures), low attrition (solid–liquid applications), deep-cleaning/sterilization (pharmaceutical applications). The main feature of uncovered, unbaffled stirred tanks is highly swirling motion of the fluid that results in a deformation of the free liquid surface. At sufficiently high agitation speeds the resulting whirlpool reaches the impeller and gives rise to a gas–liquid dispersion, so leading to the formation of a dispersion without the use of gas-sparger; the so-called self-inducing operation of the vessel. In this work, digital image analysi…
Unbaffled, Stirred Bioreactors for Animal Cell Cultivation
2017
One of the main features of animal cell bioreactors is that the cultured cells lack a strong membrane and are therefore more prone to shear damage. It is widely accepted that animal cell damage in aerated bioreactors is mainly related to burst bubbles at the air–liquid interface. A viable alternative to sparged bioreactors, aimed at minimizing cell damage, may be represented by uncovered, unbaffled, stirred tanks, which are able to provide sufficient mass transfer through the deep free surface vortex that takes place under agitation. As a consequence the need for bubble formation and subsequent bursting accompanied by cell damage is conveniently avoided. In this chapter, mass transfer perfo…